The French Institute of BioFabrication brings together companies, higher education and research institutions, university hospitals and public bodies.

In addition, the institute counts among its members personalities exercising important functions within their institutions, all strongly involved in biofabrication, but also personalities from the fields of engineering, banking or public administration. They jointly and voluntarily run the Institute.

These energies and these skills support the project of creating an international center specialised in biofabrication.

Aenitis Technologies

Aenitis Technologies was created in 2014 and develops methods of filtration, separation and manipulation of biological elements using acoustophoresis. It holds a large portfolio of patents in this field. Aenitis intends to become a world leader in a field likely to revolutionise health practices.

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Laboratoire BIO-EC

Created in 1998, Laboratoire BIO-EC is a research center specialising in efficacy studies for cosmetic and dermatological products. It develops a research activity and expertise in the safety and efficacy tests of products, food supplements and medical devices.

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Biopredic International

Biopredic International supplies tissues of human and animal origin, cells, fractions and reagents such as hepatocytes and other liver specialties, skin products, blood products and other biological fluids, non-standard human and animal tissues. Its reagents are used for in-vitro testing in the pharmaceutical, cosmetic and chemical industries. Biopredic international holds a portfolio of patents and licenses, including that concerning the human hepatic stem cell line HepaRG®.

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CCI Val-de-Marne

The Val-de-Marne Chamber of Commerce and Industry supports the development of businesses in the district. It promotes the attractiveness of the territory by creating conducive conditions for the establishment and development of businesses.

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Cellenion

Cellenion, a Scienion group company, provides solutions and technologies for controlled cell dispensing with applications in the areas of bioprinting and single-cell isolation.

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CELLforCURE

CELLforCURE is a pharmaceutical company specialised in advanced therapy drugs. Its industrial platform is one of the first and most important in Europe for the production of cell and gene therapy drugs. Created in 2013, CellforCure obtained in 2016 two certificates of good manufacturing practices (GMP) from the French National Agency for the Safety of Medicines and Health Products (ANSM) for the production of innovative therapy drugs both experimental and commercial.

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Centre Hépato-Biliaire

“Centre Hépato-Biliaire” is the main European transplant centre and one of the largest hepato-surgical centres among the hospitals of “Assistance Publique - Hôpitaux de Paris” for the care of liver and bile duct cancers as well as that of chronic liver diseases. The Centre participates in numerous clinical research programs in the fields of immunosuppression after transplants, the treatment of hepatic cancers, the follow-up of patients infected with the hepatitis virus and patients with rare liver diseases (autoimmune diseases, Wilson disease and vascular diseases). It is involved in the biofabrication of liver tissues and works closely with the University/Inserm research units located on the Paul-Brousse hospital site.

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Cosmetic Valley 

Designated a competitiveness cluster labelled by the government in 2005. Its role is to support industrials of the perfumery cosmetics sector in their commercial development and the improvement of their competitiveness. It promotes research programs in the field of in vitro and alternative tests.

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Cyprio

Cyprio’s patented technology produces 3D cellular models cultured within custom-made alginate capsules. Cyprio adresses the need for more relevant and easy to use 3D cellular models. Its flagship product, HepatoPearl®, is a physiologically relevant 3D in vitro model fabricated with its unique technology. HepatoPearls® are produced using cryopreserved and freshly isolated primary hepatocytes (human, rat...). In the longer term Cyprio also works on cartridges of microcapsules which could constitute a part of an artificial liver.

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ENS Paris-Saclay 

ENS Paris-Saclay is a higher education and research public institution. It conducts a scientific and technological research and brings together disciplines that no other institution combines in quite the same way: the natural sciences, engineering and the social sciences.

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GoLiver Therapeutics

GoLiver Therapeutics is a spin-off of Inserm and the Nantes University specializing in the development of Advanced Therapy Medicinal Products to address an urgent unmet medical need in transplantation. GoLiver Therapeutics aims to become a world leader in regenerative medicine by treating liver diseases without a transplant using differentiated pluripotent stem cells. The company was created in 2017.

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Marie Lannelongue Hospital

Marie Lannelongue Hospital is a centre of excellence in thorax, vessel and heart surgery, from newborns to adults. To treat its patients, Marie Lannelongue Hospital has long developed programs for transplanting the heart, lungs, heart-lungs in adults and children. It is the French national reference centre for complex congenital heart diseases. It is also one of the five centres of expertise in the world able to surgically treat thromboembolic pulmonary hypertension.

Marie Lannelongue is a private non-profit institution. It is a component of Paris-Saclay University. It is already engaged in studies on the reconstruction of the trachea and is developing an artificial lung. An Inserm unit is established in its premises.

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Medicen

Medicen, the Ile-de-France competitiveness cluster dedicated to health, is the unique place where SMEs and startups, major industrial players, academic research and healthcare professionals work together in order to create economic value and bring innovative solutions to the market for citizen and patient health.

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Paris-Saclay University

Paris-Saclay University is particularly renowned for the very high level of its research (1st French university in the Shanghai 2019 ranking). In particular, its research in health sciences comes to fruition in terms of therapeutic innovations. All of its research is carried out in laboratories shared with major research organisations for the most part (CNRS, Inserm, CEA, Inria, Inra). The University’s scientific environment is particularly rich in training and research in the technological field including the construction of artificial tissues and additive manufacturing.

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Sup’Biotech

Institut Supérieur des Biotechnologies de Paris (Sup’Biotech), the school of biotechnology engineers, provides multidisciplinary training in 5 years with a Master's degree or in 3 years by apprenticeship. Students benefit from a pedagogy geared towards the professional world, teamwork and international. They can either complete the 5 year course on the Paris Campus, or complete their first three years on the Lyon Campus.

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UTC

UTC is both a university and an engineering school. It is based on an interdisciplinary pedagogy and technological research oriented towards innovation. UTC trains engineers, masters and doctors able of evolving in a competitive global environment. The University of Technology of Compiègne has been working for several years with the Centre Hepato-Biliaire of Paul-Brousse Hospital on the design of an external bio-artificial liver and masters many aspects of the construction of artificial organs.

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Vallée Scientifique de la Bièvre

Vallée Scientifique de la Bièvre is a mesh of Greater Paris with an area equal to that of the city of Paris, comprising nearly 600,000 Ile-de-France residents, at the crossroads between Paris and Saclay. It includes 18 towns and 4 intercommunalities. For more than 10 years, it has combined the towns and inter-municipal authorities of Val-de-Bièvre, Sud de Seine, Hauts-de-Bièvre and Châtillon-Montrouge. Together, they develop and carry out a territorial development strategy and joint projects.

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